JAN 28, 2021

Brain Neuroplasticity, Memory Decline and Magnesium​

Neuroplasticity in the brain is how we describe the ability and variability to form new connections and store information. The brain is able to change, grow, restructure and reorganize. This allows us to adapt to the ever changing individual internal and external environment. Through a system of interconnecting networks which are formed via neuron transmission, we are able to process information. The human brain is able to not only adapt, but also to master new skills, store memories and retrieve memories.

Hence, we have Learning. This process depends on the actual formation of these connections, as well as the number of connections that are available. We do know that when synapses, the connections that allow one nerve cell to communicate with the next, are diminished, memory impairment ensues.

It is thought that this loss of synapses is an explanation for what is called “age dependent memory decline.”

Years ago, we were taught that the brain cannot heal after a traumatic injury. However, today we understand more fully the immense capability of our brains and neurological network in its ability to heal and regenerate even after a traumatic brain injury.

We have learned that synapse formation is dependent upon a variety of factors that have been well studied including insulin, ghrelin, various trophic hormones, and, as we have now learned, the ion magnesium, which enhances the activity of more than 300 enzymes.
It has now been discovered that magnesium is a critical player in the activation of nerve channels that are involved in synaptic plasticity. That means that magnesium is critical for the physiological events that are fundamental to the processes of learning and memory.

As it turns out, one form of magnesium, magnesium threonate, has the unique ability to cross the blood brain barrier so as to permeate the brain and enhance the receptors that are involved in this.
Patients have often experienced muscle relaxation, emotional calmness and peaceful sleep when taking magnesium formulas at bedtime. Researchers have demonstrated actual enhancement in the learning abilities, working memory, as well as short and long-term memory. We have seen that even quality of sleep, in laboratory animals, who were given magnesium threonate improves.


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